James Butler Puckett
October 20, 1947 ~ September 18, 2025
Born in:
Charlotte, North Carolina
Resided in:
Asheville, North Carolina
A much-loved husband, father, grandfather and brother, James Butler Puckett, 77, of Asheville, NC, passed away on September 18, 2025 with his family present.
He was born October 20, 1947 in Charlotte, NC and raised in Davidson, NC. He graduated from North Mecklenburg High School in Huntersville, NC in 1966; received a BA from Davidson College in 1970; and received his Medical Degree from UNC School of Medicine in Chapel Hill, NC in 1974. He completed a medical internship at the Medical College of Virginia in Richmond, VA in 1975. From 1975-1977, he was a Captain in the US Army Medical Corps 735th medical detachment in Sandhofen, West Germany. Upon returning to the United States, he completed his residency in internal medicine and fellowship in medical oncology at Wake Forest Bowman Gray School of Medicine in 1981.
James joined the faculty at the USC School of Medicine in Columbia, SC for three years, followed by six years on a Duke faculty assignment in Concord, NC before settling in Asheville, NC in 1990. He worked as a medical oncologist in private practice for nineteen years, notably starting one of North Carolina’s first bone marrow stem cell transplant programs in 1991. He later worked at the VA Hospital in Asheville for twelve years until his retirement in 2021.
Truly dedicated to the service of others, James volunteered his spare time at the ABCCM Free Medical Clinic and participated in a medical mission to Honduras. He was a former deacon and Sunday school teacher at the First Baptist Church in Asheville, NC.
He was known to his family and friends as an avid reader with many interests. A serial hobbyist, one could never predict the project of the year, which ranged from astronomy to Egyptian hieroglyphics to diagramming the Puckett family lineage going back several generations. Through one of these projects, James became a published author of the book “Olin, Oskeegum and Gizmo: Growing Up in a Small Southern College Town 1950-1970” (BlackInk Press 2003). He and his granddaughter enjoyed constructing increasingly large, and much to his wife’s chagrin, space-occupying Lego projects.
He is survived by his wife of 52 years, Margaret Tucker Puckett; son James William Puckett and wife Joanne Wen Puckett; granddaughter Alisa Puckett; twin brother John Lawrence Puckett and wife Karin Schaller; sister Virginia Northington Puckett Grizzard and husband William Berkeley Grizzard Jr; and nieces. He was preceded in death by his parents William Olin Puckett and Virginia Lewis House Puckett.
A memorial service will be held on Saturday, October 11, 2025, at eleven o’clock in the morning in the main sanctuary at First Baptist Church of Asheville. The family will receive friends after the service. In lieu of flowers, donations may be made in his memory to the Endowment Fund of the First Baptist Church of Asheville: FBC Asheville, 5 Oak Street, Asheville, NC 28801.
Groce Funeral Home’s Lake Julian team is assisting the family.
Services
Memorial Service: October 11, 2025 11:00 am
Room: Main Sanctuary
First Baptist Church of Asheville
5 Oak Street
Asheville, NC 28801
(828)252-4781
Funeral Home Assisting The Family:
Groce Funeral Home at Lake Julian
72 Long Shoals Road
Arden, NC 28704
(828)687-3530
http://www.grocefuneralhome.com
Asheville Butterfly Trail






I was blessed to work with Dr. Puckett for years in the Oncology practice in Asheville. He was a wonderful doctor and truly reflected Jesus Christ in his love and care for the patients and staff. Praying for the Lord to bless and comfort his family and friends.
I was blessed and fortunate to have known and worked with Dr.Puckett in the Asheville Oncology practice he was a very caring physician and always a bright light in their life’s as he treated them . He always showed compassionate and was always willing to present his Lord to them . Prayers for his family and friends in the days ahead for comfort.
James and his twin, John, were two of my favorite friends growing up in Davidson. Before he became an acclaimed doctor, he was just a special, joyful, fun friend with whom I spent many cricket- filled summer evenings- – headed to the only ice cream spot in the area- the Tastee Freeze. The three of us always had happy times as neighbors and members of the Pioneers at DCPC. I can still hear him singing loudly to “Are ye Able” in the hymnal! His joy, talent and contributions will be missed. I send my love and sincere condolences to his family.
Kristen Scott Boykin – Davidson
I was fortunate to have been Jim’s colleague twice – first as a fellow at Wake Forest, and later as one of his partners in private practice. He never told me whether to call him “James” or “Jim” so I used both names! He selflessly dedicated his immense talents to patient care, and called things the way he saw them without malice. He was an accomplished raconteur and scholar who faced each challenge with courage and a sense of humor. My sincerest condolences to his family and friends.
I also was privileged to work with Dr. Puckett for years. He was a kind and caring man and dedicated physician. He will be missed. Prayers and thoughts are with the family.
Margaret and Jim,
I worked with Dr. Puckett and was sorry to hear of his passing. James Puckett was a brilliant Oncologist.
Mary Burnette